Topic: DNA damage at the origin of cancer Title: Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice. Authors: Maier J, van Steeg H, van Oostrom C, Paschke R, Weiss RE & Krohn K. Reference: Biochimica Biophysica Acta 1773: 990-999, 2007 Summary Background Stimulation of the thyroid […]

Topic: Effects of acute bexarotene administration on TSH secretion in normal subjects Title: Single-Dose Rexinoid rapidly and specifically suppresses serum thyrotropin (TSH) in normal subjects. Authors: Golden WM, Weber KB, Hernandez TL, Sherman SI, Woodmansee WW, & Haugen BR. Reference: Journal of Clinical Endocrinology & Metabolism 92: 124-130, 2007 Summary Background Retinoid X receptor agonists […]

TOPIC: Increased risk of cardiovascular & cancer deaths from radioiodine treatment for hyperthyroidism Title: Increased cardiovascular and cancer mortality after radioiodine treatment of hyperthyroidism. Authors: Metso S, Jaatinen P, Huhtala H, Auvinen A, Oksala H, & Salmi J. Reference: Journal of Clinical Endocrinology & Metabolism 92: 2190-2196, 2007 Summary Background Although patients treated with radioiodine […]

TOPIC: Potential role for the IGF-1 receptor on T cells in Graves- disease Title: Aberrant expressions of the insulin-like growth factor-1 receptor by T cells from patients with Graves- disease may carry functional consequences for disease pathogenesis. Authors: Douglas RS, Gianoukakis AG, Kamat S, & Smith TJ. Reference: Journal of Immunology 178: 3281-3287, 2007 Summary […]